MovDisordV3, Main, Exploration, bibRecord, 005018

Effective treatment of orthostatic tremor with gabapentin

Identifieur interne : 005018 ( Main/Exploration ); précédent : 005017; suivant : 005019

Effective treatment of orthostatic tremor with gabapentin

Auteurs : Virgilio Gerald H. Evidente [États-Unis] ; Charles H. Adler [États-Unis] ; John N. Caviness [États-Unis] ; Katrina A. Gwinn [États-Unis]

Source :

Movement Disorders [ 0885-3185 ] ; 1998-09.

RBID : ISTEX:43705D34C8B868230F5C9B93E1FFF69EBA1BE36F

Descripteurs français

Pascal (Inist)
- Anticonvulsivant, Chimiothérapie, Etude cas, Gabapentine, Homme, Orthostatisme, Traitement, Tremblement.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Acetates (administration & dosage), Acetates (adverse effects), Aged, Amines, Anticonvulsant, Anticonvulsants (administration & dosage), Anticonvulsants (adverse effects), Case study, Chemotherapy, Cyclohexanecarboxylic Acids, Dose-Response Relationship, Drug, Drug Administration Schedule, Electromyography (drug effects), Female, Follow-Up Studies, Gabapentin, Human, Humans, Isometric Contraction (drug effects), Isometric tremor, Male, Middle Aged, Orthostatic tremor, Orthostatism, Postural Balance (drug effects), Posture, Shaky legs syndrome, Treatment, Tremor, Tremor (drug therapy), Weight-Bearing, gamma-Aminobutyric Acid.
MESH :
- chemical , administration & dosage : Acetates, Anticonvulsants.
- chemical , adverse effects : Acetates, Anticonvulsants.
- drug effects : Electromyography, Isometric Contraction, Postural Balance.
- drug therapy : Tremor.
- Aged, Amines, Cyclohexanecarboxylic Acids, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Follow-Up Studies, Humans, Male, Middle Aged, Posture, Weight-Bearing, gamma-Aminobutyric Acid.

Abstract

We report seven patients with orthostatic tremor (OT) who were successfully treated with the anticonvulsant gabapentin. Five of the patients had been previously tried on clonazepam, the most commonly used drug for OT, four without any benefit. The degree of improvement perceived by the patients with gabapentin varied from 60–80% (mean 73%). The effective dose of gabapentin ranged from 300–1800 mg/day (mean 1030 mg/day). The side effects were generally mild, transient, and dose‐related. Duration of response has so far ranged from 2–22 months (mean 11 months) with all patients still currently benefiting from gabapentin. We conclude that gabapentin may be an effective treatment for OT. Further trials are indicated.

Url:

https://api.istex.fr/document/43705D34C8B868230F5C9B93E1FFF69EBA1BE36F/fulltext/pdf

DOI: 10.1002/mds.870130513

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">We report seven patients with orthostatic tremor (OT) who were successfully treated with the anticonvulsant gabapentin. Five of the patients had been previously tried on clonazepam, the most commonly used drug for OT, four without any benefit. The degree of improvement perceived by the patients with gabapentin varied from 60–80% (mean 73%). The effective dose of gabapentin ranged from 300–1800 mg/day (mean 1030 mg/day). The side effects were generally mild, transient, and dose‐related. Duration of response has so far ranged from 2–22 months (mean 11 months) with all patients still currently benefiting from gabapentin. We conclude that gabapentin may be an effective treatment for OT. Further trials are indicated.</div>
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Movement Disorders (revue)

Effective treatment of orthostatic tremor with gabapentin

Effective treatment of orthostatic tremor with gabapentin

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.